Chapter 3: Introduction to Adverse Drug Reactions-II

Chapter 3: Introduction to Adverse Drug Reactions-II

Author: Ms. Neha Goel
Volume: 01
First Online: 31 August 2024
Pages: 24-35
DOI:

Abstract

Adverse drug reactions (ADRs) vary widely in their impact on patients, making the assessment of severity and seriousness crucial for appropriate management. Severity refers to the intensity of the ADR, ranging from mild, such as transient discomfort, to severe, such as life-threatening conditions or permanent disability. Seriousness, on the other hand, involves the potential consequences of the ADR, including hospitalization, significant disability, or death. Predictability assessment focuses on whether the ADR could be anticipated based on the drug’s known pharmacological profile or patient characteristics. Preventability assessment examines whether the ADR could have been avoided through proper drug selection, dosing, or monitoring. Effective management of ADRs involves promptly identifying the reaction, evaluating the risks, and taking appropriate actions, such as discontinuing the drug, adjusting the dosage, or providing supportive care. Preventative strategies, such as patient education and careful monitoring, are essential to minimize the occurrence of ADRs and ensure patient safety. Understanding these aspects of ADRs is vital for optimizing therapeutic outcomes and reducing the risk of harm to patients.

Keywords: Severity Assessment, Seriousness, Predictability, Preventability, Patient Safety, Drug Monitoring, Risk Management