{"id":5973,"date":"2024-09-03T08:08:17","date_gmt":"2024-09-03T08:08:17","guid":{"rendered":"https:\/\/demopublication.edutechy.xyz\/?p=5973"},"modified":"2025-04-26T10:23:05","modified_gmt":"2025-04-26T10:23:05","slug":"chapter-3-drugs-acting-on-autonomic-nervous-system","status":"publish","type":"post","link":"https:\/\/sproutpublication.com\/index.php\/2024\/09\/03\/chapter-3-drugs-acting-on-autonomic-nervous-system\/","title":{"rendered":"Chapter 3: Drugs Acting on Autonomic Nervous System"},"content":{"rendered":"

Author:<\/strong> Ms. Neha Goel
\nVolume:<\/strong> 01
\nFirst Online:<\/strong> 31 August 2024
\nPages:<\/strong> 49-57
\nDOI:<\/p>\n<\/div>

Abstract<\/h2><\/div>
<\/div><\/div>

Adrenergic neurotransmitters, primarily catecholamines like dopamine, norepinephrine, and epinephrine, play vital roles in the body’s response to stress and regulation of various physiological functions. The biosynthesis of catecholamines begins with the amino acid tyrosine, which is converted into LDOPA by the enzyme tyrosine hydroxylase. L-DOPA is then decarboxylated to form dopamine, which can be further hydroxylated to produce norepinephrine and finally methylated to form epinephrine. The catabolism of catecholamines involves enzymes like monoamine oxidase (MAO) and catechol-Omethyltransferase (COMT),
\nwhich break down these neurotransmitters into inactive metabolites excreted in the urine. Adrenergic receptors, classified into alpha and beta types, mediate the effects of catecholamines. Alpha receptors (\u03b11 and \u03b12) are primarily found in smooth muscles and blood vessels, where they regulate vasoconstriction and blood pressure. Beta receptors (\u03b21, \u03b22, and \u03b23) are distributed in the heart, lungs, and adipose tissue, with \u03b21 receptors increasing heart rate and contractility, \u03b22 receptors causing bronchodilation and vasodilation, and \u03b23 receptors involved in lipolysis. The precise distribution and function of these receptors enable the fine- tuning of physiological responses, highlighting the intricate balance maintained by the adrenergic system in maintaining homeostasis.<\/p>\n

Keywords:<\/strong> Adrenergic Neurotransmitters, Catecholamines, Dopamine, Norepinephrine, Epinephrine, Stress Response<\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[142],"tags":[],"class_list":["post-5973","post","type-post","status-publish","format-standard","hentry","category-medicinal-chemistry-i"],"_links":{"self":[{"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/posts\/5973","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/comments?post=5973"}],"version-history":[{"count":4,"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/posts\/5973\/revisions"}],"predecessor-version":[{"id":7385,"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/posts\/5973\/revisions\/7385"}],"wp:attachment":[{"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/media?parent=5973"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/categories?post=5973"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sproutpublication.com\/index.php\/wp-json\/wp\/v2\/tags?post=5973"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}